Sugar acids and derivatives
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
TARGETMOL CHEMICALS INC beta-Amyloid 31-35 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. beta-Amyloid (31-35) (beta-Amyloid 31-35) is the shortest sequence of native Amyloid-beta peptide. Purity 100%
Medchemexpress LLC 4-Methylumbelliferyl-β-D-xylopyranoside | 6734-33-4 | MFCD00037607 | 99.7% | 308.29 | 100 MG
4-Methylumbelliferyl-β-D-xylopyranoside (MuX) serves as a substrate for researching β-Xylosidase activity. It demonstrates burst, steady-state kinetics, indicating rapid hydrolysis of its glycosidic bonds.
- Used as a substrate for β-xylosidase activity research
- Exhibits burst, steady-state kinetics
- Supports rapid hydrolysis of glycosidic bonds
- White to off-white solid appearance
- Molecular formula: C15H16O7
- Purity of 99.7%
Medchemexpress LLC 4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside | 37067-30-4 | 99.95% | 379.36 | 1 ML
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase. The enzyme functionality is assessed by its ability to remove terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues from this compound. This product is supplied as a 10 mM solution in 1 mL of DMSO, ready for reconstitution. For optimal stability, the solution should be stored at 4°C, protected from light. Once in solvent, store at -80°C for up to 6 months or -20°C for 1 month, also protected from light.
- Fluorogenic substrate for N-acetyl-β-D-glucosaminidase
- Assesses enzyme functionality by removing terminal β-glycosidically bound N-acetylglucosamine and N-acetylgalactosamine residues
- Can be prepared in DMSO at 50 mg/mL (131.80 mM)
- Requires ultrasonication for preparation
- Newly opened DMSO is recommended due to hygroscopic nature affecting solubility
Medchemexpress LLC Beta-Cortol | 667-65-2 | 99.9% | 368.51 | 10 MG
Beta-Cortol is an O-glycosylated compound and a cortisol metabolite that can be isolated from the leaves of the mulberry cultivar Yu 711. Its concentration significantly decreases when the plant is subjected to drought stress. Beta-Cortol acts as a biomarker, with serum levels in early non-small cell lung cancer models showing a downregulation to 1/8 of the preoperative level after tumor resection. Due to these significant changes under specific pathological conditions, Beta-Cortol is extensively used in studies related to early non-small cell lung cancer.
- O-glycosylated compound and cortisol metabolite.
- Isolated from the leaves of mulberry cultivar Yu 711.
- Concentration decreases significantly under drought stress in plants.
- Serves as a biomarker for early non-small cell lung cancer.
- Serum levels are significantly downregulated in non-small cell lung cancer models after tumor resection.
Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 25 MG
BET bromodomain inhibitor 1 is an orally active and selective inhibitor of bromodomain and extra-terminal (BET) bromodomains. It demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest, inhibiting c-Myc expression, and upregulating p21 levels. Its primary applications involve research into acute myeloid leukemia, acute leukemia, and multiple myeloma.
- Orally active and selective BET bromodomain inhibitor.
- High affinity for BRD4 (IC50: 2.6 nM) and other BET bromodomains.
- Demonstrates anti-cancer activity by inducing G1-phase cell cycle arrest.
- Effective against various cancer cell lines (Kasumi 1, MM1.S, MV4-11, and RS4-11).
- Excellent selectivity for BET bromodomain family over other bromodomains.
- Does not inhibit five cytochrome P450 enzymes.
- Exhibits strong antitumor activities in in-vivo models.
Medchemexpress LLC UDP-glucuronic acid trisodium | 63700-19-6 | 5 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. It promotes the migration of liver cancer cells (Huh7, SK-Hep1, and SNU449) through induction of EMT process at concentrations of 0.5-1 mM over 24 hours.
- Critical precursor for essential glycoconjugates
- Promotes migration of liver cancer cells
- Induces EMT process in liver cancer cells
- Decreases E-cadherin and increases vimentin levels in Huh7 and SNU449 cells
eMolecules Ambeed -D-glucuronide-pNP-carbonate 100mg 847281787 A1365593 0 000 894095-98-8 913 842 C45H43N3O18
Ambeed -D-glucuronide-pNP-carbonate 100mg 847281787 A1365593 0 000 894095-98-8 913 842 C45H43N3O18
Gold Biotechnology Inc NADH Beta Reduced Sodium Salt
Reduced -nicotinamide adenine dinucleotide (NADH) plays a major role in metabolism as a cofactor in redox reactions and as a mobile electron carrier NADH is a high energy compound that donates electrons to the electron transport chain to provide energy for ATP production by oxidative phosphorylation NADH is a required oxidizing cosubstrate in fermentation which regenerates NADH is fluorescent which provides for a relatively simple way to detect NADH in biological samples NADH is also used in enzyme cycling assays to detect relevant biological molecules in tissues
Medchemexpress LLC Integrin alpha V beta 3 protein, mouse (hFc-tagged) | 20UG
Recombinant heterodimeric integrin alpha V beta 3 protein derived from mouse, produced in HEK293 cells and fused to a C-terminal human Fc (hFc) tag. Supplied as a 20 μg research reagent, it is intended for receptor-ligand interaction studies, cell adhesion assays, and signaling investigations.
- Recombinant heterodimeric integrin alpha V beta 3 derived from mouse
- Expressed in HEK293 cells to support mammalian post-translational modifications
- C-terminal human Fc (hFc) tag for purification and detection
- Suitable for receptor-ligand binding, cell adhesion, and signaling assays
- Molecular weight ranges reported for subunits: 110-135 kDa and 50-60 kDa
- Supplied as a 20 μg unit for laboratory research use
Medchemexpress LLC 4-Methylumbelliferyl β-D-cellobioside | 72626-61-0 | MFCD00063279 | 99.4% | 500.45 | 100 MG
4-Methylumbelliferyl β-D-cellobioside is a substrate for cellulase. It can be hydrolyzed to produce fluorescent 4-methylumbelliferone, which is used to study the kinetics of cellulases.
- Substrate for cellulase
- Produces fluorescent 4-methylumbelliferone
- Used to study the kinetics of cellulases
Medchemexpress LLC Integrin alpha V bet 5ug
Integrin V beta 5 proteins specifically the -V (ITGAV) subunit are multifunctional receptors for ligands such as vitronectin and fibronectin and recognize RGD sequences ITGAV ITGB3 binds fractalkine and acts as a coreceptor in CX3CR1-dependent signaling Integrin alpha V beta 8 Protein Human (HEK293 His solution) is a recombinant protein dimer complex containing human-derived Integrin alpha V beta 8 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 8 Protein Human (HEK293 His solution) has molecular weight of 187 95 kDa
Cayman Chemical 13C6-4-NItronIlIn 10mg
An internal standard for the quantification of 4-nitroaniline by GC- or LC-MS
Medchemexpress LLC Bet-in-19 | 1643947-30-1 | 99.7% | 333.39 | C19H19N5O | 10MG
BET-IN-19 is a small-molecule BET bromodomain inhibitor provided as a high-purity research reagent for epigenetic and oncology studies. It is supplied as a powder in multiple pack sizes and displays cellular activity against AML MV4-11 cells, supporting biochemical and cell-based assays. Recommended storage: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
- High purity (99.74%).
- Molecular formula C19H19N5O; molecular weight 333.39.
- Demonstrated inhibition of hIL-6 transcription and c-myc activity (IC50 ≤ 0.3 μM).
- Available in multiple pack sizes for flexible experimental design.
- Supplied as a powder with defined cold-storage stability.